Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation

Skeletal muscle myosin (SkM) has been shown to possess procoagulant activity; however, the mechanisms of this coagulation-enhancing activity involving plasma coagulation pathways and factors are incompletely understood. Here, we discovered direct interactions between immobilized SkM and coagulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Morla, Shravan, Deguchi, Hiroshi, Zilberman-Rudenko, Jevgenia, Gruber, András, McCarty, Owen J.T., Srivastava, Priyanka, Gailani, David, Griffin, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856988/
https://www.ncbi.nlm.nih.gov/pubmed/35007530
http://dx.doi.org/10.1016/j.jbc.2022.101567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856988/
https://www.ncbi.nlm.nih.gov/pubmed/35007530
http://dx.doi.org/10.1016/j.jbc.2022.101567

Ejemplares similares