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Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation
Skeletal muscle myosin (SkM) has been shown to possess procoagulant activity; however, the mechanisms of this coagulation-enhancing activity involving plasma coagulation pathways and factors are incompletely understood. Here, we discovered direct interactions between immobilized SkM and coagulation...
Autores principales: | Morla, Shravan, Deguchi, Hiroshi, Zilberman-Rudenko, Jevgenia, Gruber, András, McCarty, Owen J.T., Srivastava, Priyanka, Gailani, David, Griffin, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856988/ https://www.ncbi.nlm.nih.gov/pubmed/35007530 http://dx.doi.org/10.1016/j.jbc.2022.101567 |
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