The β-Secretase Substrate Seizure 6–Like Protein (SEZ6L) Controls Motor Functions in Mice

The membrane protein seizure 6–like (SEZ6L) is a neuronal substrate of the Alzheimer’s disease protease BACE1, and little is known about its physiological function in the nervous system. Here, we show that SEZ6L constitutive knockout mice display motor phenotypes in adulthood, including changes in g...

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Detalles Bibliográficos
Autores principales: Ong-Pålsson, Emma, Njavro, Jasenka Rudan, Wilson, Yvette, Pigoni, Martina, Schmidt, Andree, Müller, Stephan A., Meyer, Michael, Hartmann, Jana, Busche, Marc Aurel, Gunnersen, Jenny M., Munro, Kathryn M., Lichtenthaler, Stefan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857007/
https://www.ncbi.nlm.nih.gov/pubmed/34958451
http://dx.doi.org/10.1007/s12035-021-02660-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857007/
https://www.ncbi.nlm.nih.gov/pubmed/34958451
http://dx.doi.org/10.1007/s12035-021-02660-y

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