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The β-Secretase Substrate Seizure 6–Like Protein (SEZ6L) Controls Motor Functions in Mice
The membrane protein seizure 6–like (SEZ6L) is a neuronal substrate of the Alzheimer’s disease protease BACE1, and little is known about its physiological function in the nervous system. Here, we show that SEZ6L constitutive knockout mice display motor phenotypes in adulthood, including changes in g...
Autores principales: | Ong-Pålsson, Emma, Njavro, Jasenka Rudan, Wilson, Yvette, Pigoni, Martina, Schmidt, Andree, Müller, Stephan A., Meyer, Michael, Hartmann, Jana, Busche, Marc Aurel, Gunnersen, Jenny M., Munro, Kathryn M., Lichtenthaler, Stefan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857007/ https://www.ncbi.nlm.nih.gov/pubmed/34958451 http://dx.doi.org/10.1007/s12035-021-02660-y |
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