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In vitro study on effect of bardoxolone methyl on cisplatin-induced cellular senescence in human proximal tubular cells

Bardoxolone methyl [methyl-2-cyano-3, 12-dioxooleana-1, 9(11)dien-28-oate (CDDO-Me)], an activator of the nuclear factor erythroid-derived 2-related factor2 pathway, is a potential therapeutic candidate for the treatment of kidney diseases. However, its effect against cellular senescence remains unc...

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Detalles Bibliográficos
Autores principales: Kurosaki, Yoshifumi, Imoto, Akemi, Kawakami, Fumitaka, Ouchi, Motoshi, Morita, Asuka, Yokoba, Masanori, Takenaka, Tsuneo, Ichikawa, Takafumi, Katagiri, Masato, Nielsen, Rikke, Ishii, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857011/
https://www.ncbi.nlm.nih.gov/pubmed/34973124
http://dx.doi.org/10.1007/s11010-021-04295-y