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In vitro study on effect of bardoxolone methyl on cisplatin-induced cellular senescence in human proximal tubular cells
Bardoxolone methyl [methyl-2-cyano-3, 12-dioxooleana-1, 9(11)dien-28-oate (CDDO-Me)], an activator of the nuclear factor erythroid-derived 2-related factor2 pathway, is a potential therapeutic candidate for the treatment of kidney diseases. However, its effect against cellular senescence remains unc...
Autores principales: | Kurosaki, Yoshifumi, Imoto, Akemi, Kawakami, Fumitaka, Ouchi, Motoshi, Morita, Asuka, Yokoba, Masanori, Takenaka, Tsuneo, Ichikawa, Takafumi, Katagiri, Masato, Nielsen, Rikke, Ishii, Naohito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857011/ https://www.ncbi.nlm.nih.gov/pubmed/34973124 http://dx.doi.org/10.1007/s11010-021-04295-y |
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