Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells

Parkinson’s disease is a progressive neurodegenerative disorder characterized by the accumulation of misfolded alpha-synuclein in intraneuronal inclusions known as Lewy bodies and Lewy neurites. Multiple studies strongly implicate the levels of alpha-synuclein as a major risk factor for the onset an...

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Detalles Bibliográficos
Autores principales: Vasili, Eftychia, Dominguez-Meijide, Antonio, Flores-León, Manuel, Al-Azzani, Mohammed, Kanellidi, Angeliki, Melki, Ronald, Stefanis, Leonidas, Outeiro, Tiago Fleming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857012/
https://www.ncbi.nlm.nih.gov/pubmed/34984585
http://dx.doi.org/10.1007/s12035-021-02713-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857012/
https://www.ncbi.nlm.nih.gov/pubmed/34984585
http://dx.doi.org/10.1007/s12035-021-02713-2

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