Autophagy Inhibition Reduces Irradiation-Induced Subcortical White Matter Injury Not by Reducing Inflammation, but by Increasing Mitochondrial Fusion and Inhibiting Mitochondrial Fission

Radiotherapy is an effective tool in the treatment of malignant brain tumors, but irradiation-induced late-onset toxicity remains a major problem. The purpose of this study was to investigate if genetic inhibition of autophagy has an impact on subcortical white matter development in the juvenile mou...

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Detalles Bibliográficos
Autores principales: Wang, Yafeng, Xu, Yiran, Zhou, Kai, Zhang, Shan, Wang, Yong, Li, Tao, Xie, Cuicui, Zhang, Xiaoli, Song, Juan, Wang, Xiaoyang, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857090/
https://www.ncbi.nlm.nih.gov/pubmed/34962635
http://dx.doi.org/10.1007/s12035-021-02653-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857090/
https://www.ncbi.nlm.nih.gov/pubmed/34962635
http://dx.doi.org/10.1007/s12035-021-02653-x

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