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A comparative analysis of single cell small RNA sequencing data reveals heterogeneous isomiR expression and regulation

MicroRNAs (miRNAs) are non-coding small RNAs which play a critical role in the regulation of gene expression in cells. It is known that miRNAs are often expressed as multiple isoforms, called isomiRs, which may have alternative regulatory functions. Despite the recent development of several single c...

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Detalles Bibliográficos
Autores principales: Smith, Christopher Michael, Hutvagner, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857176/
https://www.ncbi.nlm.nih.gov/pubmed/35181712
http://dx.doi.org/10.1038/s41598-022-06876-3