P2X(4) deficiency reduces atherosclerosis and plaque inflammation in mice

Extracellular adenosine-5′-triphosphate (ATP) acts as an import signaling molecule mediating inflammation via purinergic P2 receptors. ATP binds to the purinergic receptor P2X(4) and promotes inflammation via increased expression of pro-inflammatory cytokines. Because of the central role of inflamma...

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Detalles Bibliográficos
Autores principales: Peikert, Alexander, König, Sebastian, Suchanek, Dymphie, Rofa, Karlos, Schäfer, Ibrahim, Dimanski, Daniel, Karnbrock, Lorenz, Bulatova, Kseniya, Engelmann, Juliane, Hoppe, Natalie, Wadle, Carolin, Heidt, Timo, Albrecht, Philipp, von Garlen, Sunaina, Härdtner, Carmen, Hilgendorf, Ingo, Wolf, Dennis, von zur Mühlen, Constantin, Bode, Christoph, Zirlik, Andreas, Duerschmied, Daniel, Merz, Julian, Stachon, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857235/
https://www.ncbi.nlm.nih.gov/pubmed/35181718
http://dx.doi.org/10.1038/s41598-022-06706-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857235/
https://www.ncbi.nlm.nih.gov/pubmed/35181718
http://dx.doi.org/10.1038/s41598-022-06706-6

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