PIK3CA co-occurring mutations and copy-number gain in hormone receptor positive and HER2 negative breast cancer

We aim to elucidate the prognostic value of PIK3CA mutations and copy number (CN) gain (PIK3CA-mut/gain) in hormone receptor-positive and HER2-negative (HR + /HER2−) breast cancer (BC). We analyzed primary HR + /HER2− BC from three publicly available datasets comprising over 2000 samples and assesse...

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Detalles Bibliográficos
Autores principales: Migliaccio, Ilenia, Paoli, Marta, Risi, Emanuela, Biagioni, Chiara, Biganzoli, Laura, Benelli, Matteo, Malorni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857304/
https://www.ncbi.nlm.nih.gov/pubmed/35181669
http://dx.doi.org/10.1038/s41523-022-00382-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857304/
https://www.ncbi.nlm.nih.gov/pubmed/35181669
http://dx.doi.org/10.1038/s41523-022-00382-5

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