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RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation

Skeletal muscle satellite cells cultured on soft surfaces (12 kPa) show improved differentiation than cells cultured on stiff surfaces (approximately 100 kPa). To better understand the reasons for this, we performed an RNA-Seq analysis for a single satellite cell clone (C1F) derived from the H2k(b)-...

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Detalles Bibliográficos
Autores principales: Richardson, Louise, Wang, Dapeng, Hughes, Ruth, Johnson, Colin A., Peckham, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857316/
https://www.ncbi.nlm.nih.gov/pubmed/35181706
http://dx.doi.org/10.1038/s41598-022-06795-3