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Sanguinarine promotes healthspan and innate immunity through a conserved mechanism of ROS-mediated PMK-1/SKN-1 activation

The longevity of an organism is influenced by both genetic and environmental factors. With respect to genetic factors, a significant effort is being made to identify pharmacological agents that extend lifespan by targeting pathways with a defined role in the aging process. Sanguinarine (San) is a be...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Wang, Haijuan, Zhu, Xinting, Jiang, Nian, Pan, Feng, Song, Changwei, Yu, Chunbo, Yu, Changyan, Qin, Ying, Hui, Jing, Li, Sanhua, Xiao, Yi, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857505/
https://www.ncbi.nlm.nih.gov/pubmed/35243236
http://dx.doi.org/10.1016/j.isci.2022.103874