Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA

SINEUPs are a novel class of natural and synthetic non-coding antisense RNA molecules able to increase the translation of a target mRNA. They present a modular organization comprising an unstructured antisense target-specific domain, which sets the specificity of each individual SINEUP, and a struct...

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Detalles Bibliográficos
Autores principales: Valentini, Paola, Pierattini, Bianca, Zacco, Elsa, Mangoni, Damiano, Espinoza, Stefano, Webster, Natalie A., Andrews, Byron, Carninci, Piero, Tartaglia, Gian Gaetano, Pandolfini, Luca, Gustincich, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857549/
https://www.ncbi.nlm.nih.gov/pubmed/35228902
http://dx.doi.org/10.1016/j.omtn.2022.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857549/
https://www.ncbi.nlm.nih.gov/pubmed/35228902
http://dx.doi.org/10.1016/j.omtn.2022.01.021

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