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Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA
SINEUPs are a novel class of natural and synthetic non-coding antisense RNA molecules able to increase the translation of a target mRNA. They present a modular organization comprising an unstructured antisense target-specific domain, which sets the specificity of each individual SINEUP, and a struct...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857549/ https://www.ncbi.nlm.nih.gov/pubmed/35228902 http://dx.doi.org/10.1016/j.omtn.2022.01.021 |