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Intraarticular injection of SHP2 inhibitor SHP099 promotes the repair of rabbit full-thickness cartilage defect

BACKGROUND: Cartilage repair has been a challenge in the field of orthopaedics for decades, highlighting the significance of investigating potential therapeutic drugs. In this study, we explored the effect of the SHP2 inhibitor SHP099, a small-molecule drug, on cartilage repair. METHODS: Human synov...

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Detalles Bibliográficos
Autores principales: Sun, Ziying, Xu, Xingquan, Lv, Zhongyang, Li, Jiawei, Shi, Tianshu, Sun, Heng, Sun, Kuoyang, Tan, Guihua, Yan, Wenqiang, Yang, Yannick Xiaofan, Wu, Rui, Xu, Jia, Guo, Hu, Jiang, Qing, Shi, Dongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857578/
https://www.ncbi.nlm.nih.gov/pubmed/35228993
http://dx.doi.org/10.1016/j.jot.2022.01.001