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Engineering autonomous closed-loop designer cells for disease therapy

Synthetic biology has made it possible to engineer mammalian cells for on-demand delivery of therapeutic agents, providing therapeutic solutions for chronic or intractable diseases. Currently, most of the engineered therapeutic cells are regulated by the administration of exogenous inducers, but the...

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Detalles Bibliográficos
Autores principales: Mahameed, Mohamed, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857602/
https://www.ncbi.nlm.nih.gov/pubmed/35243222
http://dx.doi.org/10.1016/j.isci.2022.103834