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Engineering autonomous closed-loop designer cells for disease therapy
Synthetic biology has made it possible to engineer mammalian cells for on-demand delivery of therapeutic agents, providing therapeutic solutions for chronic or intractable diseases. Currently, most of the engineered therapeutic cells are regulated by the administration of exogenous inducers, but the...
Autores principales: | Mahameed, Mohamed, Fussenegger, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857602/ https://www.ncbi.nlm.nih.gov/pubmed/35243222 http://dx.doi.org/10.1016/j.isci.2022.103834 |
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