Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer

Locally advanced rectal cancer is typically treated with chemoradiotherapy followed by surgery. Most patients do not display a complete response to chemoradiotherapy, but resistance mechanisms are poorly understood. ST6GAL-1 is a sialyltransferase that adds the negatively charged sugar, sialic acid...

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Detalles Bibliográficos
Autores principales: Smithson, Mary, Irwin, Regina, Williams, Gregory, Alexander, Katie L., Smythies, Lesley E., Nearing, Marie, McLeod, M. Chandler, Al Diffalha, Sameer, Bellis, Susan L., Hardiman, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857646/
https://www.ncbi.nlm.nih.gov/pubmed/35041825
http://dx.doi.org/10.1016/j.jbc.2022.101594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857646/
https://www.ncbi.nlm.nih.gov/pubmed/35041825
http://dx.doi.org/10.1016/j.jbc.2022.101594

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