Cargando…

Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer

Locally advanced rectal cancer is typically treated with chemoradiotherapy followed by surgery. Most patients do not display a complete response to chemoradiotherapy, but resistance mechanisms are poorly understood. ST6GAL-1 is a sialyltransferase that adds the negatively charged sugar, sialic acid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smithson, Mary, Irwin, Regina, Williams, Gregory, Alexander, Katie L., Smythies, Lesley E., Nearing, Marie, McLeod, M. Chandler, Al Diffalha, Sameer, Bellis, Susan L., Hardiman, Karin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857646/ https://www.ncbi.nlm.nih.gov/pubmed/35041825 http://dx.doi.org/10.1016/j.jbc.2022.101594

Ejemplares similares

Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase
por: Holdbrooks, Andrew T., et al.
Publicado: (2020)

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression
por: Bhalerao, Nikita, et al.
Publicado: (2023)

ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells
por: Schultz, Matthew J, et al.
Publicado: (2013)

Expression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coli
por: Ortiz-Soto, Maria Elena, et al.
Publicado: (2016)

Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death
por: Britain, Colleen M., et al.
Publicado: (2018)

Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness
por: Hait, Nitai C., et al.
Publicado: (2022)

Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli
por: Skretas, Georgios, et al.
Publicado: (2009)

ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines
por: Videira, Paula A, et al.
Publicado: (2009)

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation
por: Frommhold, David, et al.
Publicado: (2008)

Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer()()
por: Smithson, Mary, et al.
Publicado: (2022)

Phylogenetic-Derived Insights into the Evolution of Sialylation in Eukaryotes: Comprehensive Analysis of Vertebrate β-Galactoside α2,3/6-Sialyltransferases (ST3Gal and ST6Gal)
por: Teppa, Roxana E., et al.
Publicado: (2016)

Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1
por: Severino, Paulo F., et al.
Publicado: (2018)

Probing the CMP‐Sialic Acid Donor Specificity of Two Human β‐d‐Galactoside Sialyltransferases (ST3Gal I and ST6Gal I) Selectively Acting on O‐ and N‐Glycosylproteins
por: Noel, Maxence, et al.
Publicado: (2017)

Integrative View of α2,3-Sialyltransferases (ST3Gal) Molecular and Functional Evolution in Deuterostomes: Significance of Lineage-Specific Losses
por: Petit, Daniel, et al.
Publicado: (2015)

Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation
por: Kitano, Masato, et al.
Publicado: (2021)

miR-125a-5p regulates the sialyltransferase ST3GAL1 in murine model of human intestinal campylobacteriosis
por: Kraski, Angelina, et al.
Publicado: (2023)

Compound heterozygous variants within two conserved sialyltransferase motifs of ST3GAL5 cause GM3 synthase deficiency
por: Rudy, Natasha, et al.
Publicado: (2022)

ST6Gal1: Oncogenic signaling pathways and targets
por: GC, Sajina, et al.
Publicado: (2022)

Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice
por: Strekalova, Tatyana, et al.
Publicado: (2021)

Adult onset cardiac dilatation in a transgenic mouse line with Galβ1,3GalNAc α2,3-sialyltransferase II (ST3Gal-II) transgenes: a new model for dilated cardiomyopathy
por: SUZUKI, Osamu, et al.
Publicado: (2011)

Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-β1-induced EMT and confers paclitaxel resistance in ovarian cancer
por: Wu, Xin, et al.
Publicado: (2018)

ASD-like behaviors, a dysregulated inflammatory response and decreased expression of PLP1 characterize mice deficient for sialyltransferase ST3GAL5
por: Strekalova, Tatyana, et al.
Publicado: (2021)

Deficiency in ST6GAL1, one of the two α2,6-sialyltransferases, has only a minor effect on the pathogenesis of prion disease
por: Makarava, Natallia, et al.
Publicado: (2022)

α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo
por: Pérez-Garay, Marta, et al.
Publicado: (2010)

Alpha 1,3-Galactosyltransferase Deficiency in Pigs Increases Sialyltransferase Activities That Potentially Raise Non-Gal Xenoantigenicity
por: Park, Jong-Yi, et al.
Publicado: (2011)

Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer
por: Thomas, F, et al.
Publicado: (2011)

Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)
por: Ortiz-Soto, Maria Elena, et al.
Publicado: (2019)

Marine Bacterial Sialyltransferases
por: Yamamoto, Takeshi
Publicado: (2010)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli
por: Gupta, Anuj Kumar, et al.
Publicado: (2015)

A New Assay for Determining Ganglioside Sialyltransferase Activities Lactosylceramide-2,3-Sialyltransferase (SAT I) and Monosialylganglioside-2,3-Sialyltransferase (SAT IV)
por: Sun, Cynthia Q., et al.
Publicado: (2014)

Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells
por: Dorsett, Kaitlyn A., et al.
Publicado: (2019)

Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective
por: Venuto, Marzia Tindara, et al.
Publicado: (2020)

Sialyltransferase ST3GAL6 mediates the effect of microRNA‐26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway
por: Sun, Mingming, et al.
Publicado: (2017)

Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions
por: Vasconcelos, S.A. Ferreir, et al.
Publicado: (2013)

Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer
por: Jensen, Garrett L., et al.
Publicado: (2023)

Unique gangliosides synthesized in vitro by sialyltransferases from marine bacteria and their characterization: ganglioside synthesis by bacterial sialyltransferases
por: Kamimiya, Hisashi, et al.
Publicado: (2013)

Glycation Interferes with the Expression of Sialyltransferases in Meningiomas
por: Selke, Philipp, et al.
Publicado: (2021)

Direct fluorescent glycan labeling with recombinant sialyltransferases
por: Wu, Zhengliang L, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4bfdsnqnl1qcbl09o485ot5gpi