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Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes

BACKGROUND: The maternal immune system needs to tolerate the semi-allogeneic fetus in pregnancy. The adaptation occurs locally at the maternal–fetal interface as well as systemically through the maternal circulation. Failure to tolerate the paternal antigens may result in pregnancy complications, su...

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Detalles Bibliográficos
Autores principales: Bai, Kunfeng, Lee, Cheuk-Lun, Liu, Xiaofeng, Li, Jianlin, Cao, Dandan, Zhang, Li, Hu, Duanlin, Li, Hong, Hou, Yanqing, Xu, Yue, Kan, Anita S. Y., Cheung, Ka-Wang, Ng, Ernest H. Y., Yeung, William S. B., Chiu, Philip C. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857816/
https://www.ncbi.nlm.nih.gov/pubmed/35180876
http://dx.doi.org/10.1186/s12951-022-01283-2