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Human placental exosomes induce maternal systemic immune tolerance by reprogramming circulating monocytes
BACKGROUND: The maternal immune system needs to tolerate the semi-allogeneic fetus in pregnancy. The adaptation occurs locally at the maternal–fetal interface as well as systemically through the maternal circulation. Failure to tolerate the paternal antigens may result in pregnancy complications, su...
Autores principales: | Bai, Kunfeng, Lee, Cheuk-Lun, Liu, Xiaofeng, Li, Jianlin, Cao, Dandan, Zhang, Li, Hu, Duanlin, Li, Hong, Hou, Yanqing, Xu, Yue, Kan, Anita S. Y., Cheung, Ka-Wang, Ng, Ernest H. Y., Yeung, William S. B., Chiu, Philip C. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857816/ https://www.ncbi.nlm.nih.gov/pubmed/35180876 http://dx.doi.org/10.1186/s12951-022-01283-2 |
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