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Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges

The mitochondrial unfolded protein response (UPR(mt)) is an evolutionarily conserved protective transcriptional response that maintains mitochondrial proteostasis by inducing the expression of mitochondrial chaperones and proteases in response to various stresses. The UPR(mt)-mediated transcriptiona...

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Detalles Bibliográficos
Autores principales: Wang, Ge, Fan, Yumei, Cao, Pengxiu, Tan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857832/
https://www.ncbi.nlm.nih.gov/pubmed/35180892
http://dx.doi.org/10.1186/s13578-022-00747-0