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Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges
The mitochondrial unfolded protein response (UPR(mt)) is an evolutionarily conserved protective transcriptional response that maintains mitochondrial proteostasis by inducing the expression of mitochondrial chaperones and proteases in response to various stresses. The UPR(mt)-mediated transcriptiona...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857832/ https://www.ncbi.nlm.nih.gov/pubmed/35180892 http://dx.doi.org/10.1186/s13578-022-00747-0 |