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TRPV4 Inhibition Exerts Protective Effects Against Resistive Breathing Induced Lung Injury

INTRODUCTION: TRPV4 channels are calcium channels, activated by mechanical stress, that have been implicated in the pathogenesis of pulmonary inflammation. During resistive breathing (RB), increased mechanical stress is imposed on the lung, inducing lung injury. The role of TRPV4 channels in RB-indu...

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Detalles Bibliográficos
Autores principales: Toumpanakis, Dimitrios, Chatzianastasiou, Athanasia, Vassilakopoulou, Vyronia, Mizi, Eleftheria, Dettoraki, Maria, Perlikos, Fotis, Giatra, Georgia, Mikos, Nikolaos, Theocharis, Stamatios, Vassilakopoulos, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857953/
https://www.ncbi.nlm.nih.gov/pubmed/35210764
http://dx.doi.org/10.2147/COPD.S336108