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C2cd6-encoded CatSperτ targets sperm calcium channel to Ca(2+) signaling domains in the flagellar membrane

In mammalian sperm cells, regulation of spatiotemporal Ca(2+) signaling relies on the quadrilinear Ca(2+) signaling nanodomains in the flagellar membrane. The sperm-specific, multi-subunit CatSper Ca(2+) channel, which is crucial for sperm hyperactivated motility and male fertility, organizes the na...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Yeon, Wang, Huafeng, Lu, Yonggang, Ikawa, Masahito, Chung, Jean-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857959/
https://www.ncbi.nlm.nih.gov/pubmed/34998468
http://dx.doi.org/10.1016/j.celrep.2021.110226