Novel inhibitors of phosphorylation independent activity of GRK2 modulate cAMP signaling

G protein‐coupled receptors kinase 2 (GRK2) plays a major role in receptor regulation and, as a consequence, in cell biology and physiology. GRK2‐mediated receptor desensitization is performed by its kinase domain, which exerts receptor phosphorylation promoting G protein uncoupling and the cessatio...

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Detalles Bibliográficos
Autores principales: Echeverría, Emiliana, Ripoll, Sonia, Fabián, Lucas, Shayo, Carina, Monczor, Federico, Fernández, Natalia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858223/
https://www.ncbi.nlm.nih.gov/pubmed/35184416
http://dx.doi.org/10.1002/prp2.913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858223/
https://www.ncbi.nlm.nih.gov/pubmed/35184416
http://dx.doi.org/10.1002/prp2.913

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