Frequency of FLT3 Internal Tandem Duplications in Adult Syrian Patients with Acute Myeloid Leukemia and Normal Karyotype

OBJECTIVE: Activating mutations of the fms-like tyrosine kinase 3 gene (FLT3) by internal tandem duplications (ITDs) in the juxtamembrane domain (JMD) have been reported in ~30% of adult acute myeloid leukemia (AML) patients with cytogenetically normal karyotype (CN). However, FLT3/ITD mutations are...

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Detalles Bibliográficos
Autores principales: Al-Arbeed, Ismael F, Wafa, Abdulsamad, Moassass, Faten, AL-Halabi, Bassel, Al-Achkar, Walid, Abou-Khamis, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858225/
https://www.ncbi.nlm.nih.gov/pubmed/34711001
http://dx.doi.org/10.31557/APJCP.2021.22.10.3245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858225/
https://www.ncbi.nlm.nih.gov/pubmed/34711001
http://dx.doi.org/10.31557/APJCP.2021.22.10.3245

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