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Altered Epithelial-mesenchymal Plasticity as a Result of Ovol2 Deletion Minimally Impacts the Self-renewal of Adult Mammary Basal Epithelial Cells

Stem-cell containing mammary basal epithelial cells exist in a quasi-mesenchymal transcriptional state characterized by simultaneous expression of typical epithelial genes and typical mesenchymal genes. Whether robust maintenance of such a transcriptional state is required for adult basal stem cells...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Han, Yingying, Plikus, Maksim, Dai, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858298/
https://www.ncbi.nlm.nih.gov/pubmed/34984648
http://dx.doi.org/10.1007/s10911-021-09508-0