Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone regeneration in calvarial bone defects

BACKGROUND: Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in regenerative medicine. However, the efficiency of MSC transplantation and survival of engrafted stem cells remain challenging. Melatonin can regulate MSC biology. However, its function in the osteogenic differenti...

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Detalles Bibliográficos
Autores principales: Chan, Ya-Hui, Ho, Kuo-Ning, Lee, Yu-Chieh, Chou, Meng-Jung, Lew, Wei-Zhen, Huang, Haw-Ming, Lai, Pin-Chuang, Feng, Sheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858457/
https://www.ncbi.nlm.nih.gov/pubmed/35183254
http://dx.doi.org/10.1186/s13287-022-02744-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858457/
https://www.ncbi.nlm.nih.gov/pubmed/35183254
http://dx.doi.org/10.1186/s13287-022-02744-z

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