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Castration-resistant prostate cancer patient presenting with whole genome doubling with CDK-12 mutation

BACKGROUND: The use of whole-genome sequencing in clinical practice has revealed variable genomic characteristics across cancer types, one of which is whole-genome doubling (WGD), which describes the duplication of a complete set of chromosomes. Yet it is relatively rare in prostate cancer and no su...

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Detalles Bibliográficos
Autores principales: Baba, Yuto, Kosaka, Takeo, Kobayashi, Hiroaki, Nakamura, Kohei, Mikami, Shuji, Nishihara, Hiroshi, Nakanishi, Makoto, Oya, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858464/
https://www.ncbi.nlm.nih.gov/pubmed/35183184
http://dx.doi.org/10.1186/s12920-022-01178-z