Phosphorylation of BCL2 at the Ser70 site mediates RANKL-induced osteoclast precursor autophagy and osteoclastogenesis

BACKGROUND: Phosphorylation modification of BCL2 is involved in receptor activator of nuclear factor-κB ligand (RANKL)-induced autophagy of osteoclast precursors (OCPs) and osteoclastogenesis. As an antiapoptotic molecule, the role of BCL2 phosphorylation in osteoclastogenesis is unknown. This study...

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Detalles Bibliográficos
Autores principales: Ke, Dianshan, Yu, Yunlong, Li, Chenglong, Han, Junyong, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858497/
https://www.ncbi.nlm.nih.gov/pubmed/35183115
http://dx.doi.org/10.1186/s10020-022-00449-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858497/
https://www.ncbi.nlm.nih.gov/pubmed/35183115
http://dx.doi.org/10.1186/s10020-022-00449-w

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