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Excess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization

Free fatty acid derived from hyperlipidemia contributes to the development of inflammation in the pancreas. Here we explore the molecular mechanisms of fatty acid-induced pancreatitis through cellular experiments and the construction of a mouse model of hyperlipidemic pancreatitis. We found that pal...

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Detalles Bibliográficos
Autores principales: Xia, Wenwen, Lu, Zhaomin, Chen, Wei, Zhou, Jianjun, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858517/
https://www.ncbi.nlm.nih.gov/pubmed/35183119
http://dx.doi.org/10.1186/s12876-022-02146-8