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Excess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization
Free fatty acid derived from hyperlipidemia contributes to the development of inflammation in the pancreas. Here we explore the molecular mechanisms of fatty acid-induced pancreatitis through cellular experiments and the construction of a mouse model of hyperlipidemic pancreatitis. We found that pal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858517/ https://www.ncbi.nlm.nih.gov/pubmed/35183119 http://dx.doi.org/10.1186/s12876-022-02146-8 |