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Knockdown of PDX1 enhances the osteogenic differentiation of ADSCs partly via activation of the PI3K/Akt signaling pathway

BACKGROUND: Osteoporosis (OP) is a systemic bone disease manifested as low bone mass, destruction of bone microstructure, increased bone fragility and fracture risk. The purpose of this study was to explore the role and mechanism of PDX1 for osteogenic differentiation of adipose derived stem cells (...

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Detalles Bibliográficos
Autores principales: Liu, Fan, Chen, Guang-Dong, Fan, Long-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858563/
https://www.ncbi.nlm.nih.gov/pubmed/35183219
http://dx.doi.org/10.1186/s13018-021-02825-4