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The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC

BACKGROUND: Neuroendocrine prostate cancer (NEPC) is often diagnosed as a sub‐type from the castration‐resistant prostate cancer (CRPC) recurred from the second generation of anti‐androgen treatment and is a rapidly progressive fatal disease. The molecular mechanisms underlying the trans‐differentia...

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Detalles Bibliográficos
Autores principales: Lee, Cheng‐Fan, Chen, Yu‐An, Hernandez, Elizabeth, Pong, Rey‐Chen, Ma, Shihong, Hofstad, Mia, Kapur, Payal, Zhau, Haiyen, Chung, Leland WK, Lai, Chih‐Ho, Lin, Ho, Lee, Ming‐Shyue, Raj, Ganesh V, Hsieh, Jer‐Tsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858611/
https://www.ncbi.nlm.nih.gov/pubmed/35184376
http://dx.doi.org/10.1002/ctm2.695