Puerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathway

OBJECTIVE: Given the limitations of current anti-resorption agents for postmenopausal osteoporosis, there is a need for alternatives without impairing coupling crosstalk between bone resorption and bone formation ie. osteoclastogenesis. Puerarin, a unique C-glycoside isoflavonoid, was found to be ab...

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Detalles Bibliográficos
Autores principales: Qiu, Zuocheng, Li, Ling, Huang, Yuying, Shi, Keda, Zhang, Lizhong, Huang, Cuishan, Liang, Jiechao, Zeng, Qingqiang, Wang, Jiali, He, Xiangjiu, Qin, Ling, Wang, Xinluan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858883/
https://www.ncbi.nlm.nih.gov/pubmed/35228997
http://dx.doi.org/10.1016/j.jot.2022.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858883/
https://www.ncbi.nlm.nih.gov/pubmed/35228997
http://dx.doi.org/10.1016/j.jot.2022.01.003

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