Rapamycin Attenuated Zinc-Induced Tau Phosphorylation and Oxidative Stress in Rats: Involvement of Dual mTOR/p70S6K and Nrf2/HO-1 Pathways

Alzheimer’s disease is pathologically characterized by abnormal accumulation of amyloid-beta plaques, neurofibrillary tangles, oxidative stress, neuroinflammation, and neurodegeneration. Metal dysregulation, including excessive zinc released by presynaptic neurons, plays an important role in tau pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lai, Chencen, Chen, Zhuyi, Ding, Yuanting, Chen, Qian, Su, Songbai, Liu, Heng, Ni, Ruiqing, Tang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858937/
https://www.ncbi.nlm.nih.gov/pubmed/35197970
http://dx.doi.org/10.3389/fimmu.2022.782434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858937/
https://www.ncbi.nlm.nih.gov/pubmed/35197970
http://dx.doi.org/10.3389/fimmu.2022.782434

Ejemplares similares