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Rapamycin Attenuated Zinc-Induced Tau Phosphorylation and Oxidative Stress in Rats: Involvement of Dual mTOR/p70S6K and Nrf2/HO-1 Pathways

Alzheimer’s disease is pathologically characterized by abnormal accumulation of amyloid-beta plaques, neurofibrillary tangles, oxidative stress, neuroinflammation, and neurodegeneration. Metal dysregulation, including excessive zinc released by presynaptic neurons, plays an important role in tau pat...

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Detalles Bibliográficos
Autores principales:	Lai, Chencen, Chen, Zhuyi, Ding, Yuanting, Chen, Qian, Su, Songbai, Liu, Heng, Ni, Ruiqing, Tang, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858937/ https://www.ncbi.nlm.nih.gov/pubmed/35197970 http://dx.doi.org/10.3389/fimmu.2022.782434

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