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Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling

Radiation-induced lung injury is a common late side effect of thoracic radiotherapy. Endothelial dysfunction following leukocytes infiltration is a prominent feature in this process. Here, we established a clinical-mimicking mouse model of radiation-induced lung injury and found the activity of phos...

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Detalles Bibliográficos
Autores principales: Liu, Pan, Li, Yiqing, Li, Mengyao, Zhou, Hui, Zhang, Huilun, Zhang, Yuefei, Xu, Jiaqi, Xu, Yun, Zhang, Jie, Xia, Bing, Cheng, Hongqiang, Ke, Yuehai, Zhang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859005/
https://www.ncbi.nlm.nih.gov/pubmed/35243230
http://dx.doi.org/10.1016/j.isci.2022.103867