Metabolic Engineering of Saccharomyces cerevisiae for High-Level Friedelin via Genetic Manipulation

Friedelin, the most rearranged pentacyclic triterpene, also exhibits remarkable pharmacological and anti-insect activities. In particular, celastrol with friedelin as the skeleton, which is derived from the medicinal plant Tripterygium wilfordii, is a promising drug due to its anticancer and antiobe...

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Detalles Bibliográficos
Autores principales: Gao, Hai-Yun, Zhao, Huan, Hu, Tian-Yuan, Jiang, Zhou-Qian, Xia, Meng, Zhang, Yi-Feng, Lu, Yun, Liu, Yuan, Yin, Yan, Chen, Xiao-Chao, Luo, Yun-Feng, Zhou, Jia-Wei, Wang, Jia-Dian, Gao, Jie, Gao, Wei, Huang, Lu-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859104/
https://www.ncbi.nlm.nih.gov/pubmed/35198543
http://dx.doi.org/10.3389/fbioe.2022.805429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859104/
https://www.ncbi.nlm.nih.gov/pubmed/35198543
http://dx.doi.org/10.3389/fbioe.2022.805429

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