Cargando…
A43 HIGH MUC2 MUCIN BIOSYNTHESIS BY GOBLET CELLS UNDER METABOLIC STRESS PRODUCE ELEVATED LEVELS OF PRO-INFLAMMATORY CYTOKINES
BACKGROUND: The colonic mucus bilayer is an integral innate host defense mechanism that houses the commensal gut microbiota whilst protecting the underlying mucosa against harmful pathogens. This essential barrier is generated via a highly ER stressful mechanism by goblet cells that produce MUC2 muc...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859218/ http://dx.doi.org/10.1093/jcag/gwab049.042 |