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Combining Neprilysin Inhibitor With AT(2)R Agonist Is Superior to Combination With AT(1)R Blocker in Providing Reno-Protection in Obese Rats

Clinical use of the combination therapy of the neprilysin inhibitor sacubitril and angiotensin II type 1 receptor blocker valsartan is known to be associated with albuminuria. Albuminuria is both a risk factor for and an indicator of kidney injury. Earlier work from our laboratory reported that the...

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Detalles Bibliográficos
Autores principales: Gray, Elizabeth Alana, Patel, Sanket N., Doris, Peter A., Hussain, Tahir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859315/
https://www.ncbi.nlm.nih.gov/pubmed/35197849
http://dx.doi.org/10.3389/fphar.2021.778953