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Combining Neprilysin Inhibitor With AT(2)R Agonist Is Superior to Combination With AT(1)R Blocker in Providing Reno-Protection in Obese Rats
Clinical use of the combination therapy of the neprilysin inhibitor sacubitril and angiotensin II type 1 receptor blocker valsartan is known to be associated with albuminuria. Albuminuria is both a risk factor for and an indicator of kidney injury. Earlier work from our laboratory reported that the...
Autores principales: | Gray, Elizabeth Alana, Patel, Sanket N., Doris, Peter A., Hussain, Tahir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859315/ https://www.ncbi.nlm.nih.gov/pubmed/35197849 http://dx.doi.org/10.3389/fphar.2021.778953 |
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