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A52 GUT-INNERVATING TRPV1+ NEURONS DRIVE CHRONIC VISCERAL PAIN VIA MICROGLIAL P2Y12 RECEPTOR

BACKGROUND: Long-lasting changes in neural pain circuits precipitate the transition from acute to chronic pain in patients living with inflammatory bowel diseases (IBDs). While significant improvement in IBD therapy has been made to reduce inflammation, a large subset of patients continues to suffer...

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Detalles Bibliográficos
Autores principales: Defaye, M, Abdullah, N, Iftinca, M, Hassan, A, Agosti, F, Zhang, Z, Cumenal, M, Zamponi, G W, Altier, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859394/
http://dx.doi.org/10.1093/jcag/gwab049.051