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Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice

Trichuriasis is one of the most common neglected tropical diseases of the world’s poorest people. A recombinant vaccine composed of Tm-WAP49, an immunodominant antigen secreted by adult Trichuris stichocytes into the mucosa of the cecum to which the parasite attaches, is under development. The proto...

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Detalles Bibliográficos
Autores principales: Wei, Junfei, Hegde, Venkatesh L., Yanamandra, Ananta V., O’Hara, Madison P., Keegan, Brian, Jones, Kathryn M., Strych, Ulrich, Bottazzi, Maria Elena, Zhan, Bin, Sastry, K. Jagannadha, Hotez, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859434/
https://www.ncbi.nlm.nih.gov/pubmed/35197976
http://dx.doi.org/10.3389/fimmu.2022.800295