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Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice
Trichuriasis is one of the most common neglected tropical diseases of the world’s poorest people. A recombinant vaccine composed of Tm-WAP49, an immunodominant antigen secreted by adult Trichuris stichocytes into the mucosa of the cecum to which the parasite attaches, is under development. The proto...
Autores principales: | Wei, Junfei, Hegde, Venkatesh L., Yanamandra, Ananta V., O’Hara, Madison P., Keegan, Brian, Jones, Kathryn M., Strych, Ulrich, Bottazzi, Maria Elena, Zhan, Bin, Sastry, K. Jagannadha, Hotez, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859434/ https://www.ncbi.nlm.nih.gov/pubmed/35197976 http://dx.doi.org/10.3389/fimmu.2022.800295 |
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