Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria

Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill Plasmodium-infected cells. A new malaria vaccine strategy, prime-target vaccination, involves sequential viral-vectored vaccination by intramuscular and intravenous routes to target cellular immunity to the li...

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Detalles Bibliográficos
Autores principales: Noé, Andrés, Datoo, Mehreen S., Flaxman, Amy, Husainy, Mohammad Ali, Jenkin, Daniel, Bellamy, Duncan, Makinson, Rebecca A., Morter, Richard, Ramos Lopez, Fernando, Sheridan, Jonathan, Voukantsis, Dimitrios, Prasad, Naveen, Hill, Adrian V. S., Ewer, Katie J., Spencer, Alexandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859435/
https://www.ncbi.nlm.nih.gov/pubmed/35197971
http://dx.doi.org/10.3389/fimmu.2022.795463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859435/
https://www.ncbi.nlm.nih.gov/pubmed/35197971
http://dx.doi.org/10.3389/fimmu.2022.795463

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