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Distinctive Temporal Trajectories of Alzheimer’s Disease Biomarkers According to Sex and APOE Genotype: Importance of Striatal Amyloid

PURPOSE: Previously, sex and apolipoprotein E (APOE) genotype had distinct effects on the cognitive trajectory across the Alzheimer’s disease (AD) continuum. We therefore aimed to investigate whether these trajectory curves including β-amyloid (Aβ) accumulation in the cortex and striatum, and tau ac...

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Detalles Bibliográficos
Autores principales: Kim, Jun Pyo, Chun, Min Young, Kim, Soo-Jong, Jang, Hyemin, Kim, Hee Jin, Jeong, Jee Hyang, Na, Duk L., Seo, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859452/
https://www.ncbi.nlm.nih.gov/pubmed/35197846
http://dx.doi.org/10.3389/fnagi.2022.829202