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Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation

Distinct physical factors originating from the cellular microenvironment are crucial to the biological homeostasis of stem cells. While substrate stiffness and orientation are known to regulate the mechanical remodeling and fate decision of mesenchymal stem cells (MSCs) separately, it remains unclea...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Lü, Dongyuan, Zhang, Fan, Wu, Yi, Zheng, Lu, Zhang, Xiaoyu, Li, Zhan, Sun, Shujin, Long, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859489/
https://www.ncbi.nlm.nih.gov/pubmed/35198547
http://dx.doi.org/10.3389/fbioe.2021.724101