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SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling

AIMS: Aortic valve calcification is more prevalent in chronic kidney disease accompanied by hypercalcemia. Secreted protein acidic and rich in cysteine (SPARC)-related modular calcium binding 1 (SMOC1) is a regulator of BMP2 signalling, but the role of SMOC1 in aortic valve calcification under diffe...

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Detalles Bibliográficos
Autores principales: Wang, Yaqing, Gu, Jia, Du, Anning, Zhang, Siqi, Deng, Mengqing, Zhao, Rong, Lu, Yan, Ji, Yue, Shao, Yongfeng, Sun, Wei, Kong, Xiangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859632/
https://www.ncbi.nlm.nih.gov/pubmed/33757126
http://dx.doi.org/10.1093/cvr/cvab107